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Epigen™ Research Documentation Updates...


Show DivLow Carbohydrate for Increased Longevity and Youthfulness


Professor Cynthia Kenyon has conducted groundbreaking research on the effect of carbohydrates on genes.

She has concluded that carbohydrates in the diet affect two genes specifically that govern longevity and youthfulness. These genes can be found in numerous creatures – worms, monkeys, companion animals, humans, and others.

In summary, Professor Kenyon found that a carbohydrate-based diet triggered the activity of a gene that governs insulin and accelerates the aging process, while a low carbohydrate diet worked to de-activate the insulin-control gene and instead activate the gene that creates youthfulness and health. The two genes were informally dubbed the “grim reaper,” and “sweet sixteen/elixir,” respectively.

Speaking of the “Sweet Sixteen/elixir” gene (technically DAF16), Professor Kenyon explains that it “…sends out instructions to a whole range of repair and renovation genes,” and “boosts compounds that make sure the skin and muscle-building proteins are working properly, the immune system becomes more active to fight infection and genes that are active in cancer get turned off.”

This is further reinforcement of the health message Wysong has been preaching for decades – the natural model cannot be cheated or overcome. Feed a high-carbohydrate diet that is out of step with companion animals’ genetic expectation, and sickness, disease, premature aging, and the like will be the result. (The same applies to their human caretakers. See WysongHealth.net and review High Protein Uncereal™, and Whole Protein Shake.)

"Glucose shortens the lifespan of Caenorhabditis elegans by down-regulating DAF-16/FOXO activity and aquaporin gene expression." Cell Metabolism, 2009 10(5):379-91.

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Show DivHigh Protein Diet for Increased Energy and Weight Loss


A study of obese cats found that those fed a ad libitum high protein diet experienced an increase in resting and total energy expenditure over those fed a free choice moderate protein diet. This helps explain why Epigen™ is proving so beneficial for weight loss and muscle tone.

A. Wei et al., 2010. Influence of a high-protein diet on energy balance in obese cats allowed ad libitum access to food. JAPAN Online. October 2010. doi: 10.1111/j.1439-0396.2010.01062.x.

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Show DivResistant Starch Decreases Obesity


Researchers have concluded that starch that is resistant to digestion (in effect canceling dietary starch) results in decreased intestinal fat deposition and may prevent or treat obesity.

Journal of Agricultural and Food Chemistry

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Show DivAbsolute Scientific Proof Carbohydrates Are Pathogenic


“carbohydrates cause nearly all age-related diseases…high carbohydrates, which turn to glucose, hype the metabolism and trigger the release of disease-causing hormones like insulin, cotisol and adrenaline…”

Rieske, K. Absolute Scientific Proof Carbohydrates Are Pathogenic, from Absolute Truth Exposed. Boulder, Exalt Publishing, 2010.

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Show DivHigh-Carbohydrate Foods Cause Type 2 Diabetes


“...eating refined, processed, packaged high-carbohydrate foods, the disease [Type 2 diabetes] will progress until you suffer ghastly complications.”

Lecky, P. Avoid the #1 Cause of Type 2 Diabetes: Bad Food! Diabetic Warrior Newsletter, October, 2002.

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Show DivGelatin Combats Canine/Feline Epilepsy and Arthritis


Gelatin is a component of the natural, archetypal canine and feline diet. It is contained in the skin, tendons and cartilage of prey creatures. However, gelatin is lacking (or present in insufficient quantities) in most commercial pet foods.

Research shows that gelatin can be beneficial for companion animals suffering from disease conditions such as Epilepsy and Arthritis.

The entire Epigen™ line includes gelatin in amounts reflecting that which would consumed in the natural diet.

Effects of glycine and other inhibitory amino acid neurotransmitters on strychnine convulsive threshold in mice. Vet Hum Toxicol. 1985 Apr;27(2):97-9.
Anticonvulsant effects of MK-801 and glycine on hippocampal afterdischarge. Exp Neurol. 1989 May;104(2):113-7.
The glycine-prodrug, milacemide, increases the seizure threshold due to hyperbaric oxygen; prevention by 1-deprenyl. Eur J Pharmacol. 1988 Jun 10;150(3):381-4.
Age-dependent changes in brain glycine concentration and strychnine-induced seizures in the rat. Brain Res. 1989 Mar 20;482(2):247-51.
Effects of glycine and other inhibitory amino acid neurotransmitters on strychnine convulsive threshold in mice. Vet Hum Toxicol. 1985 Apr;27(2):97-9.
Anticonvulsant effects of MK-801 and glycine on hippocampal afterdischarge. Exp Neurol. 1989 May;104(2):113-7.
The glycine-prodrug, milacemide, increases the seizure threshold due to hyperbaric oxygen; prevention by 1-deprenyl. Eur J Pharmacol. 1988 Jun 10;150(3):381-4.
Age-dependent changes in brain glycine concentration and strychnine-induced seizures in the rat. Brain Res. 1989 Mar 20;482(2):247-51.


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Show DivEpilepsy and a Low Carbohydrate Diet


A 2009 study reviewed the effect of a low carbohydrate diet on the incidence of seizures in epileptic children. It was found that reducing the carbohydrate content of the diet to 40-60 grams per day significantly reduced the number of seizures, but up to as much as 66% over a period of 1 year.

Muzykewicz, D.A, et al. Efficacy, safety and tolerability of the low glycemic index treatment in pediatric epilepsy. Epilepsia. 2009;50:1118-1126.

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Show DivPea Protein Improves Lipid and Cholesterol Metabolism


Italian researchers studying the ability of pea protein to affect hepatic lipid metabolism through regulation of genes involved in cholesterol and fatty acid homeostasis concluded that consumption of pea protein results in a "marked cholesterol and triglyceride-lowering activity." Further, that "pea proteins appear to affect cellular lipid homeostasis by upregulating genes involved in hepatic cholesterol uptake and by downregulating fatty acid synthesis genes."

"Hypolipidemic Effect of Dietary Pea Proteins: Impact on Genes Regulating Hepatic Lipid Metabolism." Molecular Nutrition & Food Research, 2010;54

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Show DivSugar-Sweetened Drinks and Heart Disease


A 24-year long study has found an increasing risk of heart disease correlated with increased consumption of sugar-sweetened drinks by women.

Fung, T.T., et al. Sweetened beverage consumption and risk of coronary heart disease in women. Am J Clin Nutr. 2009;89:1037-1042.

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Show DivPolio Outbreaks Associated With Sugar Consumption


Polio outbreaks have been associated with sugar consumption. Populations of well-nourished people, who are more likely to eat sugar-rich diets, are also have an epidemic outbreak of polio. The polio virus may only present itself sporadically in populations with low consumption of refined-sugar diets.

van Meer, F. Poliomyelitis: the role of diet in the development of disease. Medical Hypothesis, 37 (3), 1992, 171-178.

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Show DivHigh Starch Intake and Cancer Recurrence


Researchers have found that a diet high in carbohydrates (starches) increases the chances of Breast Cancer recurrence.

Study participants who had a Cancer recurrence increased their daily starch intake, while those that did not experience recurrence decreased the amount of starch in their diet.

The researchers called for Cancer survivors to limit their starch intake.

There is growing awareness of the detrimental effects of high starch diets for humans. This, in spite of the fact that we have been consuming starchy foods since the advent of agriculture some 10,000 years ago. We may try, but we cannot alter our basic genetic expectation – which is tuned to eons prior to agriculture and essentially no starch. There is absolutely no logical or historical basis for carnivorous companion animals consuming a constant diet high in starch either. But this wisdom is ignored, which explains why, in staggering numbers, pets fall victim to starch-related degenerative disease conditions and illnesses.

Jennifer Emond, M.S., public health doctoral student, University of California, San Diego; Marji McCullough, Sc.D., R.D., strategic director of nutritional epidemiology, American Cancer Society; abstract, San Antonio Breast Cancer Conference, Dec. 6-10, 2011.

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Show DivHigh Protein Intake Does Not Increase the Risk of Renal Stones, Osteoporosis, Cancer, or Cardiovascular Disease


"...there is no clear evidence that a high protein intake increases the risk of renal stones, osteoporosis, cancer, or cardiovascular disease…"


Institute of Medicine, Food and Nutrition Board. Dietary reference intakes for energy, carbohydrates, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients). Washington DC: National Academy Press, 2002.

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Proteomics

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